Navigating New Fascial Plane Block CPT Codes in 2025 

The year 2025 has brought significant changes to the pain management coding world.  With the addition of CPT codes 64466-64469 and 64473-64474, providers now have distinct codes for billing thoracic fascial plane and lower extremity fascial plane services. The table below serves as a reference to the new CPT codes, along with examples of applicable anatomical locations that apply. 

Anatomical Location New CPT Code and Description 
Thoracic Fascial Plane 
• Erector Spinae 
• Pectoral 
• Quadratus Lumborum 
64466 – Thoracic fascial plane block unilateral; by injection(s), including image guidance, when performed 

64467 – Thoracic fascial plane block, unilateral; by continuous infusion(s), including image guidance, when performed 

64468 – Thoracic fascial plane block, bilateral; by injection(s), including image guidance, when performed 

64469 – Thoracic fascial plane block, bilateral; by continuous infusion(s), including image guidance, when performed 
Lower Extremity Fascial Plane 
• Fascia Iliaca 
• IPACK 
• PENG 
64473 – Lower extremity fascial plane block, unilateral; by injection(s), including imaging guidance, when performed 

64474 – Lower extremity fascial plane block, unilateral; by continuous infusion(s), including imaging guidance, when performed 

As with most CPT codes, CMS has assigned an NCCI Medically Unlikely Edit (MUE) value to these codes as of April 2025.  An MUE represents the maximum units of service reported for a HCPCS/CPT code on the majority of appropriately reported claims by the same provider/supplier for the same beneficiary on the same date of service.   

CPT Codes MUE Value MUE Adjudication Indicator Impact 
64466-64469 12These codes can only be billed once per day, per patient. 
64473-64474 13CMS will automatically deny any claim billed with one of these CPT codes in excess of 1. Medicare will consider an appeal with appropriate documentation. 

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